Ongoing Research
Center for the Genetics of Host Defense
Director
Research Interests:role of cytokines in the inflmamatory response, forward genetic analysis of immunity
Assistant Professor
Research Interests:adaptive immunity, B-cell development, forward genetics, ubiquitin-independent proteasome
Assistant Professor
Research Interests:innate immunity, forward genetics, nucleic acid sensing, toll-like receptor signaling
Assistant Professor
Research Interests:lymphocyte, calcium signaling, forward genetics, tumor resistance
Assistant Professor
Research Interests:innate immunity, forward genetics, melanoma resistance, NF-KB signaling
Assistant Professor
Research Interests:B-cell malignancy, forward genetics, proteasome activators, GTPases, RNA- and DNA-binding proteins
Assistant Professor
Research Interests:forward genetics, inflammasome regulation, tumor resistance, macrophage inflammation
Instructor
Research Interests:forward genetics, innate immunity, NLRP3 inflammasome, cell cycle regulation, obesity
Assistant Professor
Research Interests:forward genetics, T-cell immunity, cancer immunotherapy, structural immunology
Dermatology
Tamia Harris-Tryon, M.D., Ph.D.
Associate Professor
Research Interests:skin microbiome, sebaceous gland biology, lipidomics, skin steroid hormones, bacterial metabolism
Immunology
Associate Professor
Research Interests:molecular immunology, signal transduction, regulation of T-cell differentiation
Assistant Professor
Research Interests:host-pathogen interactions, genetic conflicts, positive selection, genome evolution
Department Chair
Research Interests:host-microbial interactions, mucosal immunology
Assistant Professor
Research Interests:chronic liver diseases, non-alcoholic fatty liver diseases
Assistant Professor
Research Interests:neuro-immune interactions, intestinal neural circuits, host-microbial interactions
Assistant Professor
Research Interests:host-pathogen interactions, virology, immunology, norovirus, CRISPR/Cas9 screening
Associate Professor
Research Interests:co-infection, herpes viruses, host-pathogen interaction, immunology, virology
Assistant Professor
Research Interests:immunology, microbiology, host-pathogen interactions, molecular mechanisms of immune surveillance, inflammation
Professor
Research Interests:inborn errors of immunity: from discovery to restoration
Professor
Research Interests:innate immune sensing of self vs. non-self nucleic acids, pathogenesis of autoimmune diseases
Assistant Professor
Research Interests:t cell differentiation and function, anti-viral immune response and anti-tumor immunity
Assistant Professor
Research Interests:inflammation, innate immunity, mitochondiral signaling pathways and tumor immunology
Internal Medicine
Professor & Division Chief
Research Interests:control of inflammatory responses in the intestine, inflammation and cancer progression
Professor
Research Interests:gram-negative infections in the immunocompromised host, host-pathogen interactions
Theodoros Kelesidis, M.D., Ph.D.
Associate Professor
Research Interests:HIV-associated cardiometabolic disease, host-pathogen interactions
Assistant Professor
Research Interests:antibody glycosylation, host-microbial interactions, humoral immunity, tuberculosis
Assistant Professor
Research Interests:microbiome, inflammatory bowel disease, E.coli, gut colonization, host-microbe interactions
Associate Professor
Research Interests:inflammation, tumor immunology, ubiquitionan
Hans-Christian Reinecker, M.D.
Associate Professor
Research Interests:Schlafen family proteins, immune responses by STING, cancer immunotherapy, inflammatory bowel diseases
Associate Professor
Research Interests:genetic analysis of signal-transduction pathways regulating B lymphocyte development and function
Associate Professor
Research Interests:innate immune response to intracellular pathogens, microbial pathogenesis, mucosal immunology, mycobacterium tuberculosis
Assistane Professor
Research Interests:host-viral pathogen interaction, neurotropic viruses, autophagy and innate immunity
Associate Professor
Research Interests:forward genetics, mucosal immunology, host-microbe interactions, innate immunity, vesicle trafficking
Microbiology
Professor
Research Interests:intersection between human signal-transduction and bacterial pathogenesis
Assistant Professor
Research Interests:transcription and regulation in Clostridioides difficile and other bacterial species
Professor
Research Interests:intron retention, KSHV gene expression, RNA decay, RNA methylation
Assistant Professor
Research Interests:microbiology, genetics, metagenomics, evolution, biochemistry, phage-bacterial arms race
Assistant Professor
Research Interests:virus-host interactions, invertebrate model systems, RNA/DNA virus replication
Assistant Professor
Research Interests:Genetic regulators controlling immune cell development
Professor
Research Interests:virus-host interactions and viral pathogenesis, antiviral immune responses, interferon effector mechanisms
Pathology
Assistant Professor
Research Interests:innate immunity, mucosal immunology, immunometabolism, post-translational regulation
Assistant Professor
Research Interests:Mendelian, genetics, allergy, glycosylation, autophagy, metabolism